TUIDER/23.10.2009 |
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John Hopkins University, Maryland, USA |
| Arsenic exposure, cardiovascular disease and diabetes in native americans | |
Background:
Despite suggestive experimental and epidemiologic evidence at high-chronic
arsenic exposure (=100 µg/L in drinking water), the effects of
low and moderate chronic arsenic exposure on cardiovascular and diabetes
risk are unknown. In the US, naturally occurring arsenic in drinking
water disproportionately affects rural communities of the Western States,
including Native Americans.Objective: To evaluate
the association of inorganic arsenic exposure, as determined by the
sum of inorganic and methylated arsenic species in urine, and arsenic
biotransformation with the risk of cardiovascular disease and diabetes
in 4,549 Native Americans who participated in the Strong Heart Study.
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